Heterocycles constitute the largest diversity of organic molecules of chemical, biomedical, and industrial significance. They widely exist in numerous natural products, such as vitamins, hormones, antibiotics, alkaloids, ...

Reinvestigating the synthesis of allylthiocarbamates from MBH derivatives revealed that they are obtained more efficiently from allylbromides in isopropanol rather than acetates in water. Further unlike reported, the ...

Annual Report of 2012-2013

The development in genetic engineering has led to a proliferation of large quantities and varieties of proteins, which are highly pure and free from biological contaminants. In spite of their potency and specificity ...

Elevated fatty acid levels play pathogenic role in the development of insulin resistance, associated with type 2 diabetes. Interventions with ability to ameliorate fatty acid-induced insulin resistance might be useful for ...

Streptococcus equi (S. equi) is the causative agent of the highly contagious disease ‘strangles’ in equines and zoonotic meningitis in human. Spreading of infection in host tissues is thought to be facilitated by the ...

Immune system is a complex network of interdependent cells that collectively protect the body from bacterial, parasitic, fungal, viral infections and from the growth of tumor cells. Sometimes the immune system fails to ...

A new series of coumarin based aminopyran derivatives were designed, synthesized and evaluated for their preclinical antidepressant effect on Swiss albino mice. Among the series, compounds 21, 25, 26, 27, 32 and 33 exhibited ...

The human race & natural products are coexisting since ages and their co-evolution has led to the possibility of finding new drugs for various diseases from this perpetual source-the nature. It must be emphasized that any ...

Coumarins are an important class of oxygen heterocycles which have attracted researchers in recent years because of their diverse pharmacological properties. Coumarins have important effects in plant biochemistry and ...