Theses : Recent submissions

Now showing items 141-160 of 177

Search of New Lead Bioactive Molecules with Potential for Drug Development

Shankar, Ravi (2009)

Discovering novel drugs for the treatment of human diseases is a complex process. Historically, the main source of biologically active compounds used in drug discovery programs has been natural products, isolated from ...
Redox Mechanisms in Centchroman Mediated Antineoplasticity in Human Breast Cancer Cell Lines

Ranjan, Vishal (2009)

The mere mention of the word ‘Cancer’ itself quivers our mind in general context. It is the form of cellular proliferation which escapes the body’s innate defence mechanism. It is considered as one of the major cause of ...
Synthesis of Carbohydrate Molecules of Biological Importance

Reddy, L.Vijaya Raghava (2008)

Carbohydrates represent one of the most privileged classes of naturally occurring compounds due to functional and sterochemical wealth associated with them. Besides their role as biological scaffolds and energy reservoirs ...
Studies on the structure-function relationships of membrane-active segments derived from pore forming toxin and anti-microbial peptides

Pandey, B K (2010)

Scientific community is well aware of the fact that pathogenic microorganisms are becoming resistant to conventional antibiotics at a fast pace. To circumvent this problem, efforts are now directed towards those molecules ...
Synthesis of Heterocycles of Biological Interest and their Combinatorial Chemistry

Porwal, Sharad (2009)

Leishmaniasis is a vector born disease which is caused by many species of protozoan parasite leishmania. Depending on the causative species of leishmania parasite it is found in four major clinical manifestations. These ...
Exploration of the synthetic utility of substituted 1,3-amino alcohols and allylamines for generating biodynamic agents

Nag, Somnath (2010)

The aim of the construction of diverse molecular architectures, required to serve mankind in a variety of ways, is guided by the transformation of a fundamental framework via efficient complexity-generating reactions. ...
Antidyslipidemic Activity of Curcuma longa and Glycyrrhiza glabra

Maurya, S K (2009)
Structural Studies on Protein(S) Involved in Transit Peptide Mediated Transport in Plasmodium Falciparum

Misra, Gauri (2009)

Plasmodium falciparum, the etiological agent of malaria, is the most lethal of all the protozoan parasites. The lifecycle of the parasite involves the mosquito and mammalian hosts and it faces a wide range of temperatures ...
Design & Synthesis of MCR derived Novel Nuclear Receptor Modulators as Therapeutic Agents

Maurya, Ram Awatar (2009)

Multi-component reactions (MCRs) are convergent reactions, in which three or more starting materials react to form a product, where basically all or most of the atoms contribute to the newly formed product. By nature, MCRs ...
Studies on Diversity Oriented Synthesis of Bioactive Compounds

Kumar, Shailesh (2009)

Diversity-oriented synthesis (DOS), aims to synthesize a collection of compounds that differ substantially in their molecular structure. The strategy has been proven to be an essential tool for the discovery of small bioactive ...
A Comparative Study of Estrogen Receptor Signaling under the Influence of CDRI-99/373 and SERMs

Kharkwal, Geetika (2009)

Estrogens are critical regulators of reproductive physiology and are also associated with non-reproductive effects, some of which are beneficial like improved cognitive performance and bone maintenance whereas some are ...
Expression Proteomics and Genomic Fingerprinting Studies in Sodium Antimony Gluconate (Sag) Sensitive and Resistant Clinical Isolates of Leishmania Donovani

Kumar, Awanish (2009)
Role of Nitric Oxide in Neutrophil Maturation and Function

Kumar, Sachin (2009)

Five year ago, when I started my PhD on neutrophils after completing my Master’s in Plant Biotechnology. I considered this cell an innate immune phagocyte as every student read in immunology books by Kuby and Roitt. ...
Design and synthesis of novel heterocylces as potent anticancer and anti-infective agents

Kumar, Ravi (2009)

Cancer, a group of as many as 200 diseases or disorders characterized by uncontrolled division of cells and the ability of these cells to invade other tissues. In the near past cancer has been regarded as a group of diseases ...
Functional and Structural Characterization of Actin from Leishmania donovani

Kapoor, Prabodh (2009)

“Actin is interesting”. We state this not just because actin is so plentiful that it is the single most abundant protein in many eukaryotic cells. We think that actin remains interesting because after more than 60 years ...
Synthesis of derivatives of monosaccharides for drug discovery”

Kumar, Vikas (2010)

Owing to the broad abundance in nature and the unique stereochemical and functional characteristics associated, carbohydrates are an extremely important class of compounds. There are many pharmaceutical products containing ...
Solution Structure and Dynamics of Peptidyl-Trna Hydrolase from Mycobacterium Tuberculosis H37rv

Pulavarti, S.V.S.R. Krishna (2010)
Purification and Characterization of Microbial Heparinase for Production of Low Molecular Weight Heparins (LMWHs) Acting as Antithrombotic Agents

Banga, Jaspreet (2010)

Guide- Dr. P. Kalpana Murthy, Ph D Thesis Submitted to Chhatrapati Shahu Ji Maharaj University Kanpur in 2010. Soil samples from basin of Gomti river (Lucknow, 26050’27”N, 80056’48”E), planes of northern India (Amritsar, ...
Studies on Erp (Exported Repetitive Protein, Rv3810) of M. tuberculosis H37Rv

Jha, Sidharth Shankar (2010)

The Erp (Exported Repetitive Protein, Rv3810) protein of Mycobacterium tuberculosis (Mtb) is a highly virulent secretory protein with a canonical signal sequence. It has three domains: a highly conserved amino terminal ...
Synthesis, Biological Evaluation and QSAR Studies of Novel Antimalarial Agents

Despande, shreekant (2010)

Malaria remains as one of the most devastating diseases of the developing world concentrated mainly in tropical regions. Despite the huge advances in our understanding of the disease, it continues to be one of the greatest ...

Now showing items 141-160 of 177

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