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Browsing CSIR-CDRI Theses and Dissertations by Issue Date

Browsing CSIR-CDRI Theses and Dissertations by Issue Date

Now showing items 1-20 of 177

Study the Effect of Antispermatogenic Agent- Chebulinic Acid on Male Reproductive System and Benign Prostate Hyperplasia (BPH)

Agarwal, Ankit Kumar; Sachdev, Monika (Guide) (Ph D Theses submitted by the Research Scholars of CDRI, Lucknow, 208)

Population growth is a major problem worldwide for which several control methods are currently being used that may lead to reduced total fertility rate in men and women. Overpopulation is a significant contributor to ...
Target Sites of Novel Antidiabetic Agents for the Treatment of Type 2 Diabetes Mellitus

Joshi, Maya Datt (2008)

In the last few years there have been revolutionary changes in the therapy of Diabetes mellitus. A new rapid acting insulin analog [Lys (B28), Pro (B29)] human insulin (LYSPRO) and a technique for transplantation of pancreas ...
Qsar and Modeling Studies on Antimalarial and Antitubercular Agents

Gupta, Manish Kumar (2008)

In drug research, the chemical structure and its biological response, activity, toxicity, physiological concentrations (accumulation / retention / excretion) etc. are conjoined systems. A study of these systems with respect ...
Synthetic Studies in Antimycobacterial Agents Based on Carbohydrates and Heterocycles

Singh, B K (2008)

Medicinal chemistry, an important branch of science, serving the mankind to overcome conditions unfavorable for their survival has fascinated the scientific community throughout the world. In the present scenario, development ...
Diversity Oriented Organic Synthesis of Biologically Important Molecules

Das, S K (2008)

One of the major goals in drug discovery research is to identify high affinity and specific ligands for receptors and enzymes. The identification of such ligands is an important step in the development of molecular probes ...
Design and Synthesis of CCK- 8 Derived Peptidomimetics as Selective Inhibitors of Protein Tyrosine Phosphatase 1B (PTP1B) for the Development of Anti-diabetic Agents

Sharma, Ajay (2008)

Diabetes is a disease characterized by high levels of blood glucose resulting from defects in insulin production, insulin action or both. Type 2 diabetes is typically a polygenic disease that results from a complex interplay ...
Design, Synthesis and Evaluation of Bioactive Privileged Structures for Drug Discovery

Parai, Maloy Kumar (2008)

The drug discovery process mainly depends on the discovery of compounds that cure or help to treat diseases. One of the major goals in drug discovery research is to identify high affinity and specific ligands for receptors ...
Synthesis and Antimalarial Assessment of Novel Organic Peroxides

Verma, V P (2008)

Parasitic infections are still one of the major health threats in the whole world. Malaria is a major parasitic disease, caused by a protozoan parasite of genus Plasmodium, affecting over 100 countries of the tropical and ...
Neuroprotection by inhibiting the neuronal Death Pathways In Focal Cerebral Iscchemia

Dohare, Preeti (2008)

Stroke has been defined by the World Health Organisation as “a focal (or, at times, global) neurological impairment of sudden onset, and lasting more than 24 hours (or leading to death) and of presumed vascular origin”. ...
Synthesis, Biology and Chemistry of Novel Synthetic 1, 2, 4-Trioxanes

Singh, A S (2008)

The burgeoning global problem of malaria is largely due to the emergence of parasite resistance to our limited armamentarium of antimalarial drugs. The prevalence of resistance to known antimalarial drugs has resulted in ...
Prophylactic Evaluation and Immunological Characterization of Recombinant Heavy Chain Myosin of Adult Female Brugia Malayi

Vedi, Satish (2008)

Lymphatic filariasis (LF) is a major tropical disease caused by mosquito borne parasite worm Wuchereria bancrofti, Brugia malayi or B. timori is widespread in Asia, Africa and Latin America. Of the three species, W. bancrofti ...
Synthesis of Carbohydrate Molecules of Biological Importance

Reddy, L.Vijaya Raghava (2008)

Carbohydrates represent one of the most privileged classes of naturally occurring compounds due to functional and sterochemical wealth associated with them. Besides their role as biological scaffolds and energy reservoirs ...
Synthesis of New Generation of Antimycobacterial Agents Based on Sugars and Aromatics

Saxena, Nisha (2008)

Medicinal chemistry, an important branch of chemical sciences, serving the mankind by helping them to overcome, conditions unfavorable for their survival has fascinated the scientific community throughout the world. The ...
Characterization and Modulation of the Interaction between HIV-1 Accessory Protein Nef and its Cellular Host Proteins

Gupta, Sudipti (2008)
2-Pyranones-Derived Arenes and Heteroarenes as Biodynamic Agents

Verma, Deepti (2008)

Pyran ring system is widely present in animal and plant kingdom and possesses diverse pharmacological activities. Pyran is a six-membered oxygen heterocycle with two double bonds. Out of five carbon atoms of pyran ring, ...
Studies on the Synthetic and Medicinal Application of Baylis-Hillman Chemistry

Singh, Vijay (2008)

Acquiring the capability to access structurally complex and diverse molecules through simple building blocks has been one of the underlying principles of chemical research. These diverse compounds are desired in order to ...
Studies on immunogenicity and pathogenicity of certain molecules of Brugia malayi adult worms in rodent host

Sahoo, M K (2009)
Molecular and Biochemical Characterization of Transketolase of Plasmodium falciparum

Joshi, Shweta (2009)

Malaria caused by Plasmodium falciparum (P. falciparum), a brutal killer, takes lives of about two million people every year and unfortunately most of them are non-immune children under the age of five from sub-Saharan ...
Studies on Isolated or Fused 2-Pyranones and their Nucleophile-induced Products

Chaurasia, Sumit (2009)

The choice of diabetes as a therapeutic area for research is very germane in both the national and international scenario. Diabetes is projected to increase, the world over, from 136 million in 1995 to 300 million in 2025. ...
Identification and optimization of novel inhibitors against proteinaceous drug targets from pathogenic species using in silico approaches

Dube, Divya (2009)

A drug discovery project typically starts with a pharmacological hypothesis: that the modulation of a specific biological mechanism would be beneficial in the treatment of the targeted disease. Being a part of a Structural ...

Now showing items 1-20 of 177

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