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DNA topoisomerase 2 mutant allele mildly delays the mitotic progression and activates the checkpoint protein kinase Chk1 in fission yeast

Yadav, Sudhanshu; Verma, S K; Ahmed, Shakil (2011)

DNA topoisomerases are specialized nuclear enzymes that perform topological modifications on double stranded DNA and hence are essential for DNA metabolism such as replication, transcription, recombination, condensation ...

Molecular and Pharmacological Evaluation of Central Insulin Receptors in Behavioral Responses

Agrawal, Rahul (2009)

Cloning, overexpression, purification and preliminary X-ray analysis of a Feast/famine regulatory protein (Rv2779c) from Mycobacterium tuberculosis H37Rv

Dey, Abhishek; Ramachandran, Ravishankar (2014)

Rv2779c from M. tuberculosis is a Feast/Famine regulatory protein also known as Leucine responsive regulatory protein/Asparagine synthase C- family (Lrp/AsnC) of transcriptional regulators. This class of proteins is known ...

Cu-Catalyzed Conversion of Propargyl Acetates to E-α,β-Unsaturated Amides via Ketenimine Formation with Sulfonyl Azides

Kumar, Y K; Kumar, G R; Reddy, M S (2014)

The reaction between readily accessible propargyl acetates and sulfonyl azides in presence of CuI catalyst yielded trans α, β-unsaturated N-tosylamides via N-sulfonyl ketimine formation followed by a probable 1,3-OAc ...

Some Indian Traditional Medicinal Plants with Antioxidant Activity: A Review

Katiyar, Shikhar; Patidar, Devendra; Gupta, Shailja; Singh, R K; Singh, Poonam (2013)

Since the beginning of human civilization, a number of Indian medicinal plants have been used in the traditional system of medicine (Ayurveda), aiming to maintain health and to cure diseases. Oxidative stress has emerged ...

An actin-like protein is involved in regulation of mitochondrial and flagellar functions as well as in intramacrophage survival of Leishmania donovani

Singh, Kuldeep; Veluru, N K; Trivedi, Vishal; Gupta, C M; Sahasrabuddhe, A A (2014)

Actin related proteins are ubiquitous actin-like proteins that show high similarity with actin in terms of their amino acid sequence and three-dimensional structure. However, in lower eukaryotes, such as trypanosomatids, ...

Studies of rpf (Resuscitation Promoting Factor) genes of Mycobacterium tuberculosis

Yadav, Amita (2009)

Transcriptional Analysis of Macrophage Response to Tuberculosis Infection on Treatment with Biodegradable Microparticles Containing Anti-TB Drugs

Yadav, Awadh Bihari (2009)

Design and Synthesis of DPP-IV Inhibitors as Anti-diabetic Agents

Sethi, Nidhi (2010)

Diabetes is a disease characterized by high levels of blood glucose resulting from defects in insulin production, insulin action or both. Type 2 diabetes is typically a polygenic disease that results from a complex ...

Design and Synthesis of some Anti-tubercular compounds & Studies in C-C bond forming reactions

Sikriwal, Dimpy (2010)

It is now widely appreciated that bacterial resistance to antibiotics has grown to very serious proportions. Many formerly controlled infectious diseases are no longer readily treatable with contemporary antibiotics, ...

Biochemical and Molecular Targets of Novel Antidiabetic Agents

Singh, Amar Bahadur (2009)

Antileishmanial treatment using chemotherapy in combination with immunomodulators in experimental Visceral Leishmaniasis

Sane, Shraddha A. (2010)

Leishmaniases, in its variety of visceral (VL), cutaneous (CL) and mucocutaneous (MCL) forms, directly affects about 2 million people per annum, with approximately 350 million individuals at risk worldwide. During the last ...

Characterization of Myosin protein(s) of Leishmania donovani

Santha Ram, K S (2009)

Identification and Characterization of Sigma Factor F of Mycobacterium smegmatis

Singh, A K (2009)

Isolation And Characterization Of Antimicrobial Metabolites From Microbial Isolates

Singh, Vineeta (2009)

Antibiotic resistance has become a serious problem in both the developed and developing nations. The incidence of antibiotic resistance among the infectious microorganisms is fairly high the available antibiotics have ...

Role of drug metabolizing enzymes and glutathione system in development of drug resistance in Plasmodium yoelii

Rizvi, Amber (2010)

“A disaster not just on its way but already happening”. This statement was made by Kevin Marsh in Lancet while talking about malaria. This disease is indeed a disaster that has plagued humanity since ancient times and is ...

Studies on immunogenicity and pathogenicity of certain molecules of Brugia malayi adult worms in rodent host

Sahoo, M K (2009)

Purification and characterization of adult Brugia malayi antigen: identification and immunoprophylactic evaluation of protective molecule/s

Shakya, Shilpy (2009)

Molecular and Biochemical Studies on Hexokinase of Filarial Parasite

Singh, Alok Ranjan (2009)

Search of New Lead Bioactive Molecules with Potential for Drug Development

Shankar, Ravi (2009)

Discovering novel drugs for the treatment of human diseases is a complex process. Historically, the main source of biologically active compounds used in drug discovery programs has been natural products, isolated from ...

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