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http://hdl.handle.net/123456789/74
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| Title: | Regioselective Synthesis of Functionally Crowded Benzenes at Room Temperature through Ring Transformation of 2H-Pyran-2-ones |
| Authors: | Singh, Fateh V
Kumar, Vijay
Goel, Atul |
| Keywords: | 2H-pyran-2-one
benzene
malononitrile
ring transformation reaction. |
| Issue Date: | 2007 |
| Citation: | Synlett (2007), 2086 |
| Series/Report no.: | C.D.R.I. Communication No 7224 |
| Abstract: | An expeditious synthesis of highly substituted benzenes with electron withdrawing or donating substituents is described and illustrated by carbanion-induced ring transformation of 2H-pyran-2-one with malononitrile in excellent yield. The novelty of the reaction lies in the creation of an aromatic ring at room temperature from six membered-lactones under mild reaction conditions. |
| URI: | http://hdl.handle.net/123456789/74 |
| Appears in Collections: | Medicinal and Process Chemistry
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| atulgoel-Synlett-2007-2086.pdf | | 136Kb | Adobe PDF | View/Open |
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