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| Title: | 4beta-Chloroethylaminopyrimidines and the formation of imidazolidino [1,2-c] pyrimidines on acid treatment of 4-bis-beta-hydroxyethylaminopyrimidines |
| Authors: | Nagpal, K L
Dhar, M M |
| Keywords: | 4-beta-chloroethylamino
4-bis-beta-chloroethylamino
pyrimidines
2-chloro-4-bis-beta-hydroxyethylaminopyrimidine |
| Issue Date: | 1967 |
| Citation: | Tetrahedron, 1967,23,1297 |
| Abstract: | During synthesis aimed at obtaining 4-beta-chloroethylamino and 4-bis-beta-chloroethylamino pyrimidines, it has been found that treatment of 2-chloro-4-bis-beta-hydroxyethylaminopyrimidine with hydrochloric acid or of 4-bis-beta-hydroxyethylamino-2-mercaptopyrimidine with chloroacetic acid and hydrochloric acid yields 1-beta-hydroxyethyl-5-oxo-imidazolidino [1.2-c] pyrimidine. |
| URI: | http://hdl.handle.net/123456789/558 |
| Appears in Collections: | Medicinal and Process Chemistry
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| mmdhar-tetrahedron-23-1967-1297.pdf | | 1550Kb | Adobe PDF | View/Open |
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