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http://hdl.handle.net/123456789/528
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| Title: | Solid - Phase Peptide Synthesis of [L--Alanine3-L-isoleucine5] angiotensin II |
| Authors: | Khosla, MC
Smeby, RR
Bumpus, FM |
| Keywords: | Angiotensim II
peptide synthesis
copolystyrene-divinylbenzene
Alanine3-L-isoleucine5 |
| Issue Date: | 1967 |
| Citation: | Biochemistry, 6,1967, 754 |
| Abstract: | [Alanine3-L-isoleucine5] angiotensin II was synthesized by stepwise elongation of the peptide chain on copolystyrene-divinylbenzene using dicyclohexylcarbodiimide as the condensing agent. The purified end product was obtained in 55% yield and possessed 68% of the pressor activity of [isoleucine5]- angiotensim II. |
| URI: | http://hdl.handle.net/123456789/528 |
| Appears in Collections: | Medicinal and Process Chemistry
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| fmbumpus-6-1967-754.pdf | | 999Kb | Adobe PDF | View/Open |
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