Digital Knowledge Repository of Central Drug Research Institute, Lucknow (India) >
Publications of CDRI Scientists >
Medicinal and Process Chemistry >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/494
|
| Title: | A versatile synthesis of dihydropyrimidinone c-nucleosides |
| Authors: | Mishra, R C
Katiyar, Diksha
Tewari, Neetu
Tripathi, R P |
| Issue Date: | 2005 |
| Citation: | Nucleosides, Nucleotides & Nucleic Acids (2005), 24,15–35 |
| Series/Report no.: | CDRI Communication No. 6338 |
| Abstract: | A versatile syntheses of N-aryl dihydropyrimidinone C-nucleosides (20-29) is described. Glycosyl amino esters (3-9), obtained by reductive arylation of glycosyl amino esters 1 and 2, on condensation with different isocyanates afforded respective ureidyl derivatives (10-19) in good to quantitative yields. The latter on cyclative amidation with a combination of DBU/ tetra butyl ammonium bromide/ 4Å MS gave the respective nucleosides (20-29) in good yields. |
| URI: | http://hdl.handle.net/123456789/494 |
| Appears in Collections: | Medicinal and Process Chemistry
|
Files in This Item:
| File |
Description |
Size | Format |
|---|
| Nucleosides, Nucleotides, and Nucleic Acids, 24, 15–35, 2005.pdf | | 154Kb | Adobe PDF | View/Open |
|
All items in DSpace are protected by copyright, with all rights reserved.
|
