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| Title: | An efficient regioselective synthesis of functionalized biphenyls via sequential reactions of aromatic aldehydes and β-keto esters or ketones |
| Authors: | Anindra Sharma
Jyoti Pandey
R P Tripathi |
| Keywords: | Polysubstituted benzenes
Aldol reactions
Michael additions
Knoevenagel reaction
Regioselective
Hydroxylated biphenyls |
| Issue Date: | 2009 |
| Citation: | Tetrahedron Letters (2009) 50, 1812-1816 |
| Series/Report no.: | CDRI Communication No 7552 |
| Abstract: | Knoevenagel/ Michael/ Aldol reactions of aromatic aldehydes and β-keto esters/ketones in a sequential manner yielded the intermediate cyclohexanones in good yields. The latter on oxidative aromatization with iodine afforded the functionalized biphenyls with at least one phenolic hydroxyl in moderate to good yields |
| URI: | http://hdl.handle.net/123456789/490 |
| Appears in Collections: | Medicinal and Process Chemistry
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| Tetrahedron Letters 50 _2009_ 1812–1816.pdf | | 149Kb | Adobe PDF | View/Open |
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