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http://hdl.handle.net/123456789/482
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| Title: | Highly convenient regioselective synthesis of functionalized arylated benzene from ketene-S,S-acetal under mild conditions at room temperature |
| Authors: | Kumar, Vijay
Singh, Fateh V
Parihar, Amrita
Goel, Atul |
| Keywords: | Ketene-S
S-acetal
2H-Pyran-2-one
Arylated benzene
Molecular propeller
Quinquephenyl |
| Issue Date: | 2009 |
| Citation: | Tetrahedron Lett. (2009) 50, 680-683 |
| Series/Report no.: | CDRI Communication No 7254 |
| Abstract: | A general, highly efficient synthesis of arylated benzenes from simple stitching of alpha-oxo-ketene-S,S-acetals and functionalized deoxybenzoins via a ‘lactone intermediate’ is described. This procedure offers easy access to highly functionalized arylated benzenes containing sterically demanding groups in good to excellent yields. The advantage of the procedure lies in the fabrication of arylated benzenes with desired conformational flexibility along the molecular axis at room temperature and in a transition metal-free environment through easily accessible precursors. |
| URI: | http://hdl.handle.net/123456789/482 |
| Appears in Collections: | Medicinal and Process Chemistry
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| Tetrahedron Lett.,2009, 50, 680-683.pdf | | 129Kb | Adobe PDF | View/Open |
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