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http://hdl.handle.net/123456789/443
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| Title: | Stabilization of β-hairpin structures via inter-strand π-π and hydrogen bond interactions in α-, β-, γ-hybrid peptides |
| Authors: | Chakraborty, Tushar Kanti
Rao, K Srinivasa
Kiran, M Udaya
Jagadeesh, B |
| Keywords: | pyrrole amino acid
furan amino acid
peptidomimetics
β-hairpin |
| Issue Date: | 2009 |
| Citation: | Tetrahedron Letters, 50,4350-4353 |
| Series/Report no.: | CDRI Communication No.7774 |
| Abstract: | Synthesis and conformational studies of α-, β-, γ-hybrid peptides containing a pyrrole amino acid (Paa, 1) and a furan amino acid (Faa, 2), namely Boc-β-Phe-Faa-D-Pro-Gly-Paa-β-HGly-Faa-OMe (3) and Boc-Paa-β-Phe-Faa-D-Pro-Gly-Paa-β-HGly-Faa-OMe (4), were carried out and they adopt -hairpin structures stabilized via inter-strand π-π and hydrogen bonding interactions. |
| URI: | http://hdl.handle.net/123456789/443 |
| Appears in Collections: | Medicinal and Process Chemistry
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| tkchakraborty-7774-2009-tetlett-50-4350.pdf | | 210Kb | Adobe PDF | View/Open |
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