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http://hdl.handle.net/123456789/334
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| Title: | Synthesis of azatricyclodiones & octahydro-benzo[f]isoindoles and their antimicrobial evaluation |
| Authors: | Saxena, Nisha
Singh, Nimisha
Mishra, Mridul
Keshava, G B Shiva
Shukla, P K
Tripathi, R P |
| Keywords: | Cycloaddition
dienophile
furfuryl amine
azatricyclodiones
octahydro-benzo[f]isoindoles |
| Issue Date: | 2008 |
| Citation: | JEIMC 23,476-482 (2008) |
| Abstract: | A series of azatricyclodiones and octahydro-benzo[f]isoindoles have been synthesized by (4+2) Diels-Alder cycloaddition of maleimides with furfuryl amine. Reaction of azatricyclodiones with isocyanates led to respective ureides. All of the compounds were screened against a number of bacteria and fungi. One of the compounds (2) displayed moderate Antitubercular activity while two compounds (2) and (4) inhibited the fungal growth at 25 µg/mL. |
| URI: | http://hdl.handle.net/123456789/334 |
| Appears in Collections: | Medicinal and Process Chemistry
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| JEIMC, 2008, 23 , 476-482.pdf | | 127Kb | Adobe PDF | View/Open |
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