Digital Knowledge Repository of Central Drug Research Institute, Lucknow (India) >
Publications of CDRI Scientists >
Medicinal and Process Chemistry >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/21
|
| Title: | A regioselective palladium-free protocol for accessing unsymmetrical biaryls through ring transformation of 6-aryl-~-pyrones |
| Authors: | Kumar, Amit
Singh, Fateh V
Goel, Atul |
| Keywords: | asymetric synthesis
regioselective
6-aryl-a-pyrones
carbanion-induced ring |
| Issue Date: | 2007 |
| Citation: | Tetrahedron Letters 48 (2007) 7283-7286 |
| Series/Report no.: | C.D.R.I. Communication No. 7255 |
| Abstract: | A regioselective synthesis of unsymmetrical biaryls with electron withdrawing or donating substituents is described and
illustrated by carbanion-induced ring transfonnation of 6-aryl-a-pyrones with methoxyacetone in excellent yield. Our methodology is
an alternative to classical organometal-catalyzed aryl-aryl coupling reactions and can be applied to the synthesis of functionally
demanding naphthyl biaryls for the development of new ligands for asymetric synthesis |
| URI: | http://hdl.handle.net/123456789/21 |
| Appears in Collections: | Medicinal and Process Chemistry
|
Files in This Item:
| File |
Description |
Size | Format |
|---|
| atulgoel-tetlett-48-7283.pdf | | 90Kb | Adobe PDF | View/Open |
|
All items in DSpace are protected by copyright, with all rights reserved.
|
