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| Title: | Highly Substituted Isoxazoles: The Baylis-Hillman reaction of substituted 4-isoxazolecarbaldehydes and attempted cyclization to isoxazole-annulated derivatives |
| Authors: | Roy, Amrendra K
Batra, Sanjay |
| Keywords: | Baylis-Hillman reaction
DABCO
DMAP.
4-isoxazolecarboxaldehyde |
| Issue Date: | 2003 |
| Citation: | Synthesis (2003)1347-1356 |
| Series/Report no.: | CDRI Communication Number 6389 |
| Abstract: | In an attempt to understand the effect of position of the formyl group on the efficiency of Baylis-Hillman reaction within isoxazolecarboxaldehydes, the reactions of substituted 4-isoxazolecarboxaldehydes to obtain highly substituted isoxazoles are described. Attempts to obtain isoxazole-annealed derivatives from these Baylis-Hillman adducts involving SNR’-SNAr substitu-tion strategy are also described. |
| URI: | http://hdl.handle.net/123456789/20 |
| Appears in Collections: | Medicinal and Process Chemistry
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| sbatra-6389-SYNTHESIS-2003-1347.pdf | | 139Kb | Adobe PDF | View/Open |
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