Digital Knowledge Repository of Central Drug Research Institute, Lucknow (India) >
Publications of CDRI Scientists >
Medicinal and Process Chemistry >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/19
|
| Title: | New cassane butenolide hemiketal diterpenes from the marine creeper Caesalpinia honduc and their
antiproliferative activity |
| Authors: | Yadav, Prem P
Arora, Ashish
Bid, Hemant K
Konwar, Rituraj
Kanojiya, Sanjeev |
| Issue Date: | 2007 |
| Citation: | Tetrahedron Letters 48 (2007) 7194-7198 |
| Series/Report no.: | CDRI Communication Number 7219 |
| Abstract: | Two new cassane butenolides, caesalpinolide A (1) and B (2), epimeric at the hemiketal position were isolated from the
marine creeper Caesalpinia bonduc. The structures were elucidated by the analysis of spectroscopic data and relative stereochemistry was assigned on
the basis of ROESY correlations. Compounds 1 and 2 were found to inhibit MCF-7 breast cancer cell lines with ICso values of (IlM)12.8 and 6.1, respectively, along with the inhibition of endometrial and cervical cancer cell lines |
| URI: | http://hdl.handle.net/123456789/19 |
| Appears in Collections: | Medicinal and Process Chemistry
|
Files in This Item:
| File |
Description |
Size | Format |
|---|
| ppyadav-tetlett-48-7194.pdf | | 199Kb | Adobe PDF | View/Open |
|
All items in DSpace are protected by copyright, with all rights reserved.
|
