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| Title: | Functional Drug Targeting to Erythrocytes In Vivo using Antibody Bearing Liposome as Drug Vehicles |
| Authors: | Agrawal, Ajay K
Singhal, Arun
Gupta, C M |
| Issue Date: | 1987 |
| Citation: | Biochemical and Biophysical Research Communications (1987), 148, 357-361 |
| Series/Report no.: | CDRI Communication No. 4131 |
| Abstract: | Covalent attachment of anti-erythrocyte F(ab')2 to the liposome surface has recently been shown to considerably enhance tne liposome binding to erythrocytes in vivo. These antibody bearing liposomes have nPW been found quite effect1ve-as-vehicles for delivering the antimalarial drug., chloroquine. to erythrocytes in Plasmodium berghei-infected mice. This demonstrates
the usefulness of antibody targeted liposomes as carriers for site-specific
drug de1ivery. |
| URI: | http://hdl.handle.net/123456789/123 |
| Appears in Collections: | Molecular & Structural Biology
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| cmg-BBRC-1987-148-357.pdf | | 1358Kb | Adobe PDF | View/Open |
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